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(CNN) — Local security forces and coalition soldiers killed two Taliban leaders and several other insurgents Thursday in western Afghanistan, NATO’s International Security Assistance Force said.

Taliban leaders Haji Dawlat Khan and Haji Nasrullah Khan and a “significant number of other insurgents” were killed during “a successful operation against high-priority Taliban targets” in Herat province, according an ISAF statement.

The soldiers and local security forces also freed a number of men “handcuffed and imprisoned in appalling conditions” in a compound belonging to the insurgents, the ISAF said.

The rescued men are receiving medical care, and there was no evidence of civilian casualties in the operation, according to the ISAF.

The incident reflects increasing violence between troops and Taliban militants across Afghanistan and comes as U.S. commanders request more troops there.

Since May, the deaths of U.S. and allied troops have far outpaced such deaths in Iraq. As of Thursday, the toll in Afghanistan since May was 21 compared to seven in Iraq.

A soldier died Thursday of noncombat-related causes in southern Afghanistan, but the ISAF did not provide that soldier’s nationality.

On Sunday, nine U.S. troops were killed in an attack on a combat outpost in eastern Afghanistan.

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